Projects

kConFab Letter of Intent Submissions

Date	Investigators	Affiliation	Project Title
September 2009, due March 2010 pilot application	Stephen Fox & Gillian Mitchell	Peter MacCallum Cancer Centre, Melbourne	The identification of BRCA germline mutations using immunhistochemistry
September 2009, due March 2010 full application	Sunil Lakhani	Royal Brisbane Hospital, Brisbane	Expression of CT-X antigens in familial breast cancer
Nov 2009 Due May 2010 Full Application	Paul James, Gillian Mitchell, Alison Trainer, Judy Kirk, John Hopper; Melissa Southey, Stephen Fox, Ian Campbell	Peter MacCallum Cancer Centre, University of Melbourne, Westmead Hopital Sydney	Focus on pancreatic cancer
December 2009, due June 2010 Full application	Melissa Southey & David Goldgar	The University of Melbourne & The Utah University, USA	Breast Cancer Susceptibility Gene Discovery through targeted and whole exome sequencing in High-risk BCFR families.
February 2010 Pilot application	Ashok Venkitaraman et al	Hutchison/MRC Research Centre, University of Cambridge, UK	Germline BRCA2 mutation carriers are at an increased risk of pancreatic ductal adenocarninoma.
March 2010 Full Application	Stuart MacGregor	QIMR, Royal Brisbane Hospital, Brisbane	Identifying markers of risk and outcome in ovarian and breast cancer via efficient evaluation of epigenetic changes in non-cancerous tissue.
March 2010, due September 2010 Full Application	John Hopper, Kelly Phillips et al	The University of Melbourne & The Peter MacCallum Cancer Centre, Melbourne	Statistical analysis of an international 10 year prospective family study of gene-environment interactions on risk of female breast cancer.
May 2010 Full Project due November 2010	Alison Trainer, Paul James, Gillian Mitchell, James Dowty, John Hopper	Peter MacCallum Cancer Centre and The University of Melbourne	Male Breast Cancer
April, due October 2010 Full Application	James Flanagan	Imperial College, London	Identification of novel breast cancer subgroups by DNA methylation
June 2010, due December 2010 Full application	Jonathan Beesley, Roger Reddel, Sharon Johnatty, Hilda Pickett	Queensland Institute of Medical Research & Children's Medical Research Institute, NSW	The TERT locus as a susceptibility gene for ovarian and breast cancer: genetic and functional evaluation
June 2010, due December 2010 Full Project	Sally Hunter, Ian Campbell, Anna DeFazio	Peter MacCallum Cancer Centre, Melbourne, Westmead Hospital, Sydney	High resolution genome-wide SNP and copy number analysis of genetic
June 2010, due December 2010 Full application	Georgia Chenevix-Trench, Kum Kum Khanna, David Goldgar, Emma Whitelaw & Nick Hayward	QIMR, Royal Brisbane Hospital, Brisbane	Mutations in genes that modify epigenetic silencing in familial breast cancer
July 2010, due January 2011 Full application	Kum Kum Khanna, Georgia Trench, Sunil Lakhani	QIMR, Royal Brisbane Hospital, Brisbane	Immunohistochemcial analysis of DNA damage repair proteins in familial breast cancers.
July 2010, due January 2011 Full application	Kelly Bolton and Stephen Chanock	National Cancer Institute USA & Cambridge University, UK	Detecting Rare Variants for Ovarian Cancer in the 19p13 region.
July 2010, due January 2011 Full Application	Steve Linke	Prelude, Inc USA	DCIS clinicopathologic characteristics.

A pilot or full application must be made within 6 months of submitting the letter of intent. If more than six months has elapsed, a new letter of intent must be submitted prior to the full application.