Familial Aspects of Cancer
Research and Practice 2022
30th August - 2nd September 2022


Australian Colorectal Cancer Family Study
Australian Breast Cancer Family Study
Family Cancer Clinics of Australia and New Zealand
International Sarcoma Kindred Study
kConFab


Latest News
Pink Hope QLD ~ Information & Support Day. Saturday 16th July 2022.
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Latest Publications
Multiple ABCB1 transcriptional fusions in drug resistant high-grade serous ovarian and breast cancer. Nature Communications 2019.
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Shared heritability and functional enrichment across six solid cancers. Nature Communications. Jan 2019.
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Do BRCA1 and BRCA2 gene mutation carriers have a reduced ovarian reserve? Protocol for a prospective observational study. BMJ Open. Nov 2019.
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About kConFab

The Kathleen Cuningham Foundation Consortium for Research into Familial Aspects of Breast Cancer (kConFab) brings together geneticists, clinicians, community representatives, surgeons, genetic counsellors, psychosocial researchers, pathologists and epidemiologists from all over Australia and New Zealand who believe the causes and consequences of familial predisposition to breast cancer can be understood only by a concerted national effort at both the basic and clinical level.

In 1997, kConFab, with the help of the Family Cancer centres in Australia and New Zealand began enrolling families with a strong history of breast and breast/ovarian cancer. Genetic, epidemiological, medical and psychosocial data collected from these families by kConFab are stored in a de-identified fashion in a central relational database. Biospecimens collected from family members are used to characterise germ-line mutations in predisposing genes such as BRCA1, BRCA2, ATM, PALB2, p53, PTEN. kConFab has accumulated data on more than 1,900 multigenerational, multi-case kindreds.

kConFab itself is not a research organisation in the usual sense, but rather provides a resource upon which researchers can draw. The aims of the consortium are to make data and biospecimens widely available to researchers for use in peer-reviewed, ethically-approved funded research projects on familial aspects of breast cancer. At present, kConFab is supplying biological specimens and data to more than 180 research projects world wide.

kConFab Questions and Answers

Information on the organisation and structure of kConFab.
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